Comparative and Functional Screening of Three Species Traditionally used as Antidepressants: Valeriana officinalis L., Valeriana jatamansi Jones ex Roxb. and Nardostachys jatamansi (D.Don) DC.

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Iridoids and sesquiterpenoids from the roots of Valeriana jatamansi Jones.

Three new iridoids, jatamanvaltrates R-S (1-2) and jatamanin Q (3), as well as three new sesquiterpenoids, valeriananoids D-E (4, 5) and clovane-2β-isovaleroxy-9α-ol (6), together with nine known compounds were isolated from the roots of Valeriana jatamansi Jones. Compound 2 was the first reported iridoid with fatty acid esters in the Valerianaceae family. The structures of new compounds were e...

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Standardization and Preliminary Phytochemical Screening of Nardostachys Jatamansi Dc. Rhizome

The plant Nardostachys jatamansi DC. (Valerianaceae) is a critically endangered rhizome bearing medicinal herb. It is restricted to specialized habitats in high altitudes of Himalaya ranging from 3000 to 5000m. Nardostachys jatamansi has been traditionally employed in treatment of wide range of disorders including nervous system, digestive system, circulatory system, respiratory system, urinary...

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Anti-epileptic Effects of Valepotriate Isolated from Valeriana jatamansi Jones and Its Possible Mechanisms

OBJECTIVE This work aimed to investigate the anti-epileptic effects of valepotriate isolated from Valeriana jatamansi Jones and studied its possible mechanisms. METHODS The anti-epileptic effects of valepotriate were studied using maximal electroshock-induced seizure (MES), pentylenetetrazole (PTZ)-induced epilepsy, and pentobarbital sodium-induced sleeping model in mice. The possible anti-ep...

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A comparative pharmacological study on the effect of Tagara (Valeriana wallichii) AND Jatamansi (Nardostachys jatamansi) in the management of anidra w.s.r to primary insomnia

The present study was undertaken to evaluate Tagara and Jatamansi for certain CNS activities to ascertain the basis for their use as a sedative and hypnotics. The drugs were evaluated for hypnotic and sedative, anti anxiety, anti depressant and anti psychotic activities using standard experimental protocol. The data generated suggests that the test drugs Tagara and Jatamansi have complex CNS ac...

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Essential Oil Composition of Valeriana Jatamansi Jones from Himalayan Regions of India

Valeriana jatamansi Jones germplasm collected from sub-temperate Himalayan region of Uttarakhand and North-East state of Meghalaya, India was evaluated under identical conditions at National Bureau of Plant Genetic Resources, Bhowali, India, to study germplasm diversity based on essential oil composition. Twenty one compounds were identified in V. jatamansi root oil by GC and GC-MS. The major c...

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ژورنال

عنوان ژورنال: Plants

سال: 2020

ISSN: 2223-7747

DOI: 10.3390/plants9080994